[摘要]目的 分析甘肅省某三甲醫(yī)院類風(fēng)濕關(guān)節(jié)炎（RA）患者發(fā)病特征及生命質(zhì)量，為RA的診治和預(yù)后評(píng)估提供臨床依據(jù)。方法 回顧性統(tǒng)計(jì)分析蘭州大學(xué)第一醫(yī)院風(fēng)濕免疫科2011年1月至2014年1月收治的244例RA患者病歷資料，并對(duì)所有入組患者進(jìn)行電話隨訪。結(jié)果 本項(xiàng)研究發(fā)現(xiàn)RA患者男女比例約為1:3；年齡分布上46~60歲最多，占44.7%（109/244）；蘭州市患者比較多，占42.64%；職業(yè)分布中工人及農(nóng)民的比例較高，分別為31.97%和29.92%；45%的患者手關(guān)節(jié)X線出現(xiàn)RA改變；早期（病程<6月）確診的RA比例最高占46.31%。隨訪結(jié)果顯示，有效隨訪103（42.21%）例。62例（60.19%）緩解，41例（39.81%）處于疾病活動(dòng)期；影響RA患者生命質(zhì)量的因素為年齡、性別、目前居住地、醫(yī)療費(fèi)用支付方式、職業(yè)、首次確診時(shí)間、一級(jí)親屬RA家族史、疾病活動(dòng)程度及出院后治療方式。結(jié)論 應(yīng)盡早明確診斷，加強(qiáng)RA患者的疾病知識(shí)教育及醫(yī)患溝通，為RA患者確定合理的個(gè)體化治療方案，使RA患者接受長(zhǎng)期正規(guī)的抗風(fēng)濕治療及隨訪，才能切實(shí)改善患者的預(yù)后和生命質(zhì)量。

    [關(guān)鍵詞] 類風(fēng)濕關(guān)節(jié)炎；發(fā)病特征；生命質(zhì)量

Study on Characteristics and Quality Of Life of the Patients with Rheumatoid Arthritis in a Tertiary Grade Hospital. Chen Yanfei, Wu Jirong, the First Hospital of Lanzhou University, Li Rheumatism Lead，Lanzhou 730000, Gansu,2. The First Clinical Medical College of Lanzhou University, Lanzhou 730000, Gansu.

    [Abstract] objective To analyze the characteristics and quality of life of patient with rheumatoid arthritis (RA) in a tertiary hospital of Gansu province. Then we can provide clinical evidence to the diagnosis and prognostic evaluation of RA. Methods To retrospective statistical analyze the record of 244 RA patients admitted in the First Hospital of Lanzhou University from January 2011 to January 2014. All the patients were followed up by phone. Results In this study we find that proportion of men and women in RA is about 1:3; The age distribution of 46 to 60 years old is 44.7% (109/244);There are more patients in Lanzhou,42.64%.The proportion of workers and farmers in the occupational distribution is most. It is 31.97% and 29.92%. 45 percent of the patients had hand joint RA changes by X-ray films. The highest percentage of cases diagnosed in the early stage was 46.31 percent. Follow-up results show that the effective follow-up is 103 cases (42.21%), in which 62 cases are alleviated (60.19%), and 41 cases (39.81%)are in disease activity. The life quality of patients with RA is related with age, gender, current residence, payment of medical charges, occupation, time of first confirmed diagnosis, family history of RA diagnosis, extent of disease activity and treatment after discharged. Discussion We should confirm diagnosis early, strengthen the disease knowledge education and doctor-patient communication, to make reasonable individualized treatment plan for RA patients, to help the RA patients receive long-term regular anti-rheumatism treatment and follow-up, which can improve the prognosis for patients and their quality of life.

    [key words] rheumatoid arthritis; Onset of characteristic; Quality of life